Reishi Mushroom Extract
Latin: Ganoderma lucidum
D.Atkinson Mushroom Extracts
All of our mushroom extracts are produced for us by Martin Powell. Our products are practitioner strength and are produced to the highest standards.
Martin is a biochemist and a Chinese herbalist who has worked with mushroom nutrition for over 20 years. He lectures at the University of Westminster and is the author of MedicinalMushrooms - a Clinical Guide.
As well as running a clinical practice he continues to research mushrooms health benefits and runs seminars on their clinical uses for doctors and health care professionals in the UK and
The information below is intended for educational use and is not meant to be used to diagnose or treat any medical condition. Anyone who is experiencing any symptoms, has been diagnosed with or suspects they may have a medical condition should contact a medical doctor or appropriately qualified health professional.
From Medicinal Mushrooms - A Brieft Guide By Martin Powell:
Main active components
Reishi’s wide-ranging health benefits are due to its combination of highly active immune-modulating
polysaccharides and over 130 triterpenoid compounds (primarily ganoderic and lucidenic acids), with actions including: anti-inflammatory, antihistamine, sedative, anti-hypertensive and anti-cancer1.
Reishi has traditionally been associated with the Taoist quest for immortality, as well as being used to treat a range of health conditions, including: cancer, heart disease and bronchitis.
Main Health Benefits
Reishi has a long history of use in cancer treatment with many reports of spontaneous remission2.
Although both polysaccharides and triterpenes contribute to Reishi’s anti-cancer action, clinical
trials have focussed exclusively the more easily characterised polysaccharide extracts, with a recent
review of 5 randomised controlled trials indicating that patients given Reishi polysaccharide extracts
were 1.27 times more likely to respond positively to chemo/radiotherapy than those without3. At
the same time, Reishi’s triterpenes also show extensive anticancer activity, inhibiting cancer cell
growth, inducing apoptosis (cell death) and, in the case of prostate cancer cells, blocking androgen
Reishi’s combination of high immuno-modulatory activity with strong anti-inflammatory and antihistamine
activity make it a uniquely suitable supplement for those suffering from allergies such as
hayfever (allergic rhinitis)5. By addressing both the underlying immune imbalance that predisposes
the body to overreacting to pollen or other allergens, as well as the histamine-mediated inflammatory responses that result, it can be used to both help alleviate the symptoms and
prevent their development.
Reishi’s combination of immunomodulatory and anti-inflammatory action also makes it a useful supplement for a range of inflammatory auto-immune conditions, such as rheumatoid arthritis, psoriasis or ulcerative colitis.
The traditional name ‘spirit mushroom’ points to the sedative action of Reishi’s triterpenoid
Improvements in sleep patterns are one of the most commonly reported effects of Reishi
supplementation and it is frequently prescribed for this purpose6.
Reishi has long been a popular traditional treatment for liver diseases and demonstrates wide
• Protection from chemical toxicity
• Inhibition of liver fibrosis
• Normalisation of liver enzymes
• Reduction in inflammation
Traditionally used in the treatment of heart disease, Reishi has been shown to support cardiovascular health through cholesterol-lowering, blood-pressure lowering and anticoagulant effects, with improvements in ECG, chest pain, palpitations and shortness of breath reported in one randomized, double-blind, multi-centred study using a polysaccharide extract at 5.4g/day7.
As well as its benefits for cardiovascular health, Reishi has traditionally been used to treat bronchitis,
with older patients showing particular benefit. Its anti-allergic properties mean that it is helpful for
allergic asthma, while Chinese studies also report alleviation of altitude sickness8.
Classically differentiated according to six different colours, today virtually all cultivated Reishi is Red Reishi, with the term Duanwood Red Reishi sometimes being used to refer to cultivation on whole logs, as opposed to cultivation on ‘logs’ made of compressed sawdust.
Reishi’s uniquely broad health benefits are due to its combination of immune-modulating, water-soluble polysaccharides and antiinflammatory triterpenes, which are poorly water-soluble. In order to deliver high levels of both polysaccharides and triterpenes, supplements may combine both
polysaccharide-rich hotwater and triterpene-rich ethanolic (alcohol-based) extracts. Alternatively,
some supplements use Reishi spores, which also contain high levels of triterpenes, with oil-based
spore extracts containing up to 30%.
Supplementation levels of Reishi products can vary considerably owing to the range of product types available. Most trials using polysaccharide extract have been at 5.4g/day, while daily consumption of pure Reishi powder can be considerably higher. Products combining Reishi polysaccharides and triterpenes typically have dosage ranges of 1-3g/day, Reishi sporoderm-broken spore products 3-5g/day and Reishi spore oil extracts 500-1,500mg/day. Reishi’s triterpenes have been reported to have anti-coagulant properties and supplements containing high levels should be usedwith caution by those on blood-thinning medication.
1. Ganoderma - a therapeutic fungal biofactory. Paterson RR. Phytochemistry. 2006; 67(18):1985-
2. Anticancer effects of Ganoderma lucidum: a review of scientific evidence. Yuen JW, Gohel MD.
Nutr Cancer. 2005;53(1):11-7.
3. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Jin X, Ruiz Beguerie J, Sze DM, Chan
GC. Cochrane Database Syst Rev. 2012 Jun 13;6:CD007731.
4. Ganoderma lucidum and its pharmaceutically active compounds. Boh B, Berovic M, Zhang J, Zhi-
Bin L. Biotechnol Annu Rev. 2007;13:265-301.
5. The use of Ganoderma lucidum (Reishi) in the management of Histamine-mediated allergic
responses. Powell M. The Nutrition Practitioner. October 2004.
6. A preliminary study on the sleep-improvement function of the effective ingredients of Ganoderma
lucidum fruitbody. Jia W, Wu M, Zhang JS, Liu YF. Acta Edulis Fungi. 2005;12(3):43-47.
7. A phase I/II study of ling zhi mushroom Ganoderma lucidum (W.Curt.:Fr.) Lloyd
(Aphyllophoromycetideae) extract in patients with coronary heart disease. Gao Y, Chen G, Dai X,
Ye J, Zhou S. Int J Med Mushrooms 2004;6(4):30.
8. Medicinal Mushrooms - An Exploration of Tradition, Healing and Culture. Hobbs C. 1986. Pub.
Botanica Press, Williams. p. 96-107.
If you are taking any other medication, or have any health issues please check with one of our qualified medical herbalists before using one of our herbal products. Seek advice if pregnant.
Max Dose: Add 1-3g daily to food or drink as part of a balanced diet (one level 5ml teaspoon = 2g)
Reishi (Ganoderma lucidum). Medicinal quality aqueous and ethanolic extract (30% polysaccharides/3% triterpens)
UK Shipping and Delivery
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Most orders will arrive within 5 working days.
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