Re-Cha Mushroom Blend
Medicinal quality aqueous and ethanolic extract (30% polysaccharides/ 3% triterpins)
Max dose: Add 1-3g daily to food or drink as part of a balanced diet (one level 5ml teaspoon = 2g)
Medicinal Mushrooms - A brief guide written by Martin Powell.
Martin is a biochemist and a Chinese herbalist who has worked with mushroom nutrition for over 20 years. He lectures at the University of Westminster and is the author of Medicinal Mushrooms - a Clinical Guide. As well as running a clinical practice he continues to research mushrooms health benefits and runs seminars on their clinical uses for doctors and health care professionals in the UK and world wide. D.Atkinson Mushroom Extracts All of our mushroom extracts are produced for us by Martin Powell. Our products are practitioner strength and are produced to the highest standards.
Disclaimer: The information below is intended for educational use and is not meant to be used to diagnose or treat any medical condition. Anyone who is experiencing any symptoms, has been diagnosed with or suspects they may have a medical condition should contact a medical doctor or appropriately qualified health professional.
Reishi’s wide-ranging health benefits are due to its combination of highly active immune-modulating polysaccharides and over 130 triterpenoid compounds (primarily ganoderic and lucidenic acids), with actions including: anti-inflammatory, antihistamine, sedative, anti-hypertensive and anti-cancer1.
Reishi has traditionally been associated with the Taoist quest for immortality, as well as being used to treat a range of health conditions, including: cancer, heart disease and bronchitis.
Main Health Benefits
Cancer: Reishi has a long history of use in cancer treatment with many reports of spontaneous remission2. Although both polysaccharides and triterpenes contribute to Reishi’s anti-cancer action, clinical trials have focussed exclusively the more easily characterised polysaccharide extracts, with a recent review of 5 randomised controlled trials indicating that patients given Reishi polysaccharide extracts were 1.27 times more likely to respond positively to chemo/radiotherapy than those without3. At the same time, Reishi’s triterpenes also show extensive anticancer activity, inhibiting cancer cell growth, inducing apoptosis (cell death) and, in the case of prostate cancer cells, blocking androgen receptors4.
Allergies: Reishi’s combination of high immuno-modulatory activity with strong anti-inflammatory and anti- histamine activity make it a uniquely suitable supplement for those suffering from allergies such as hayfever (allergic rhinitis)5. By addressing both the underlying immune imbalance that predisposes the body to overreacting to pollen or other allergens, as well as the histamine-mediated inflammatory responses that result, it can be used to both help alleviate the symptoms and prevent their development.
Auto-immune disease: Reishi’s combination of immunomodulatory and anti-inflammatory action also makes it a useful supplement for a range of inflammatory auto-immune conditions, such as rheumatoid arthritis, psoriasis or ulcerative colitis.
Insomnia/anxiety: The traditional name ‘spirit mushroom’ points to the sedative action of Reishi’s triterpenoid components. Improvements in sleep patterns are one of the most commonly reported effects of Reishi supplementation and it is frequently prescribed for this purpose6.
Liver disease: Reishi has long been a popular traditional treatment for liver diseases and demonstrates wide hepatoprotective properties,including:
• Protection from chemical toxicity
• Inhibition of liver fibrosis
• Normalisation of liver enzymes
• Reduction in inflammation
Cardiovascular health: Traditionally used in the treatment of heart disease, Reishi has been shown to support cardiovascular health through cholesterol-lowering, blood-pressure lowering and anticoagulant effects, with improvements in ECG, chest pain, palpitations and shortness of breath reported in one randomized, double-blind, multi-centred study using a polysaccharide extract at 5.4g/day7.
Respiratory health: As well as its benefits for cardiovascular health, Reishi has traditionally been used to treat bronchitis, with older patients showing particular benefit. Its anti-allergic properties mean that it is helpful for allergic asthma, while Chinese studies also report alleviation of altitude sickness8.
Classically differentiated according to six different colours, today virtually all cultivated Reishi is Red Reishi, with the term Duanwood Red Reishi sometimes being used to refer to cultivation on whole logs, as opposed to cultivation on ‘logs’ made of compressed sawdust.
Reishi’s uniquely broad health benefits are due to its combination of immune-modulating, water-soluble polysaccharides and antiinflammatory triterpenes, which are poorly water-soluble. In order to deliver high levels of both polysaccharides and triterpenes, supplements may combine both polysaccharide-rich hotwater and triterpene-rich ethanolic (alcohol-based) extracts. Alternatively, some supplements use Reishi spores, which also contain high levels of triterpenes, with oil-based spore extracts containing up to 30%.
Supplementation levels of Reishi products can vary considerably owing to the range of product types available. Most trials using polysaccharide extract have been at 5.4g/day, while daily consumption of pure Reishi powder can be considerably higher. Products combining Reishi polysaccharides and triterpenes typically have dosage ranges of 1-3g/day, Reishi sporoderm-broken spore products 3-5g/ day and Reishi spore oil extracts 500-1,500mg/day. Reishi’s triterpenes have been reported to have anti-coagulant properties and supplements containing high levels should be usedwith caution by those on blood-thinning medication.
References: 1. Ganoderma - a therapeutic fungal biofactory. Paterson RR. Phytochemistry. 2006; 67(18):1985- 2001. 2. Anticancer effects of Ganoderma lucidum: a review of scientific evidence. Yuen JW, Gohel MD. Nutr Cancer. 2005;53(1):11-7. 3. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Cochrane Database Syst Rev. 2012 Jun 13;6:CD007731. 4. Ganoderma lucidum and its pharmaceutically active compounds. Boh B, Berovic M, Zhang J, Zhi- Bin L. Biotechnol Annu Rev. 2007;13:265-301. 5. The use of Ganoderma lucidum (Reishi) in the management of Histamine-mediated allergic responses. Powell M. The Nutrition Practitioner. October 2004. 6. A preliminary study on the sleep-improvement function of the effective ingredients of Ganoderma lucidum fruitbody. Jia W, Wu M, Zhang JS, Liu YF. Acta Edulis Fungi. 2005;12(3):43-47. 7. A phase I/II study of ling zhi mushroom Ganoderma lucidum (W.Curt.:Fr.) Lloyd (Aphyllophoromycetideae) extract in patients with coronary heart disease. Gao Y, Chen G, Dai X, Ye J, Zhou S. Int J Med Mushrooms 2004;6(4):30. 8. Medicinal Mushrooms - An Exploration of Tradition, Healing and Culture. Hobbs C. 1986. Pub. Botanica Press, Williams. p. 96-107.
Main active components
Unusually among medicinal mushrooms, Chaga’s most important components are derived from the bark of the host birch trees on which it grows. Chief among these are a large number of betulinic acid derivatives and melano-glucan complexes. Traditional use Revered as a folk medicine, especially among the peoples of eastern Russia, Chaga has traditionally been boiled to make a tea, which is drunk to treat a range of conditions, including: cancers, viral and bacterial infections and gastro-intestinal disorders1, 2.
Main Health Benefits
Cancer: Betulinic acid shows wide-ranging anti-cancer activity, including against: leukaemia, malignant brain and peripheral nervous system cancers for which mushroom polysaccharide-based supplements show limited benefit3. As with other mushrooms, Chaga’s polysaccharide components also show strong immune-modulating activity and this combination of mushroom polysaccharides with host- derived betulinic acid contributes to Chaga’s traditional use in cancer treatment, including
FOR: inoperable breast, lip, gastric, parotid, lung, skin, colorectal cancer and Hodgkin lymphoma1.
Digestive disorders: Melano-glucan complexes have wide antimicrobial activity and Chaga has traditionally been used as an internal cleanser with Befungin, an alcohol extract of Chaga, licensed in Russia for the treatment of stomach and intestinal disorders1.
Psoriasis: Several anecdotal reports indicate benefit of Chaga for psoriasis and this is supported by a Russian study on 50 psoriasis patients, which reported a 76% cure rate, with improvement in a further 16% of cases. The same study reported that it typically took 9-12 weeks for improvement to become apparent4.
Chaga supplements need to be made from wild-harvested Chaga if they are to contain the main active components derived from the bark of the host birch trees. Although most traditional use is based on hot-water extracts (teas), the triterpenoid betulinic acid derivatives (although not the polysaccharides) are more soluble in alcohol and for this reason tinctures or other alcohol-based extracts are sometimes used, either on their own or in combination with polysaccharide-rich hot- water extracts. Traditionally around 5g of Chaga would be ground and boiled to make a tea, while the recommended daily dose of Befungin is 1tsp, three times a day and for extracts 1-3g/day.
References: 1. The Chaga Storey. Spinosa R. 2006. The Mycophile, 47:1. 2. Plants used against cancer. Hartwell JL. 1982. Quartermain Pubs: Lawrence, Mass. p.694. 3. Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection. Cichewicz RH, Kouzi SA. Med Res Rev. 2004;24(1):90- 114. 4. Treatment of Psoriasis with Using Chaga Mushroom Preparations. Dosychev EA, Bystrova VN. 1973. Vestn Dermatol Venerol. May;47(5):79-83.
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